Effect of hyperbilirubinemia on Some Physiological parameters in infantile in Karbala city

Authors

  • Qasim Hamadi Abid Pathological analysis department, College of applied medical science, university of Karbala,Karbala, Iraq

DOI:

https://doi.org/10.61132/obat.v2i6.879

Keywords:

hyperbilirubinemia, hemoglobin and packed cell volume

Abstract

Given that these substances' levels are essential for informing medical
personnel about the body's reaction to the different treatments being
administered, this study was planned to assessment some physiological
variations to infants infected with hyperbilirubinemia. This will help the
medical staff manage the condition properly with lower morbidity and
mortality. In this study, 60 patients and 40 healthy controls (clinically
evaluated by a specialist physician) are selected from males who are only
1 year old. This study conducted in Al-hussein medical city Hospital in
Karbala city. This study showed that significant decrease in weight,
hemoglobin and packed cell volume in patients in comparison with
healthy, while noted significant increase in total white blood cells in
patients comparison with healthy, while showed there are insignificant
change in red blood cells and platelet.

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References

-Watchko JF .( 2006). Neonatal hyperbilirubinemia . what are the risks ? N. Eng. J Med , p 354 (18) : 1947-1949.

-Sgro M; Campbell D; Shah V. (2006).Incidence and causes of severe neonatal hyperbilirubinemia in Canada. CMAJ, p 175(6):587-90.

-Parks, D.K., Montgomery, D., & Yetman, R.J. (2000). Perinatal conditions: Jaundice. In C.E. Burns, M.A. Brady, A.M. Dunn, & N.B. Starr (Eds.), Pediatric primary care. (2nd ed.) (pp. 1172-1216). Philadelphia: W.B. Saunders Company.

-Hayes, G. (2000). The jaundiced newborn: Minimizing the risks. Patient Care, 34(2), 45-56.

-Seidman DS, Moise J, Ergaz Z, et al. (2000). A new blue light-emitting phototherapy device: a prospective randomized controlled study. J Pediatr.;136 ,p771 –774.

-Newman, TB; Liljestrand, P; Escobar; GJ. (2005) .Combining clinical risk factors with serum bilirubin levels to predict hyperbilirubinemia in newborns. Arch Pediatr Adolesc Med, 159:113.

-Dennery PA; Seidman DS, Stevenson DK.(2001). Neonatal hyperbilirubinemia. N Engl J Med,p 344:581.

-Harris, M.C.; Bernbaum, J.C.; Polin, J.R.; Zimmerman, R.; & Polin, R.A. (2001). Developmental follow-up of breastfed term and near term infants with marked hyperbilirubinemia.Pediatrics,107(5),1075-87.

-Liang L ; Zhou Y ; Xiao Q ; Yan T and Xu X .(2008). Development and evalution of a reverse dot blot assay for the simultaneous detection of six common Chinese G6PD mutations and one polymorphism . Blood cells , Molecules and Diseases , 41 (1) : 17-21 .

-Bhutani VK; Johnson LH; Maisels MJ, et al. (2004). Kernicterus: epidemiological strategis for its prevention through systems-based approaches. J Perinatol,24:650-62.

-Paula Bolton - Maags ; Angela Thomas .(2007). hematology and bone marrow disease, Neil McIntosh, Peter Helms, Rosalind Smyth, 144.Fofar and Arneil’s textbook of pediatrics, 7th edition , Churchill Livingstone , p 1070- 1073 .

-Antonio Do Rego . (2008).Thalassemia , Disease diagnosis ; The crux volume . volume , May / Jun , 2-3 .

-Seema Tyagi ; M. Kabra ; N. Tandon; R. saxena , et al . (2003 ).clinico hematological profile of thalassemia intermedia patients . int. J. hum Genets 3(4) ,p251- 258 .

-Stoll BJ. (2007).Blood disorders. In: Kliegman RM, Behrman RE, Jenson HB, StantonBF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier;:chap 103.

-Camilla R; Martin and john P. (2004). neonatal hyperbilirubinemia in Manual of neonatal care 5th ed. Lippincott Williams and Wilkins, Philadelphia, 185-220.

-Sgro M; Campbell D; Shah V. (2006).Incidence and causes of severe neonatal hyperbilirubinemia in Canada. CMAJ, p 175(6):587-90.

-Carmoklly H. Elshujeery T. A. (2000).Causes and management of neonatal hyperbiliryubinemia a (thesis) submitted to scientific council of pediatrics in partial fulfillment for the degree of fellowship of Iraqi commission for medical specialization in pediatrics.

-Berkowitz, C.D. (2000). Pediatrics: A primary care approach (2nd ed.). Philadelphia: W.B. Saunders Company.

-Mao Jean M .D. (2005).Jaundice and hemolytic disease of the newborn infants, neonatal division, department of pediatrics, Article in internet.

-Ip, S, Chung; M, Kulig; J, et al. (2004).An evidence-based review of important issues concerning neonatal hyperbilirubinemia. Pediatrics, 114:e130.

-AAP.(2004)Clinical Practice Parameter Subcommittee on Hyperbilirubinemia: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation. Pediatrics; 114: 297-316.

-Anthony J Piazza and Barbara J Stoll. (2007). Jaundice and hyperbilirubinemia in the newborn In : Behrman RE,Nelson Textbook of pediatrics .18th ed. Philadelphia: Saunders,756-774.

-SPSS Statistical Packages for the Social Sciences. (2001): Statistical software for windows version 13.0 Micrisoft. SPSS, Chicago, IL, USA.

-Abdul-Razzaq YM .(1999). Diversity in expression of glucose-6-phosphate dehydrogenase deficiency in females . Clin Genet , 55 (1) : 13-9 .absorption in patients receiving total parenteral nutrition.

-Alexander, D.C., & Robin, B. (2000). Neonatology: Unconjugated hyperbilirubinemia in the newborn. In G.K. Sieberry, & R. Iannone (Eds.), The Harriet Lane handbook (15th ed.). St. Louis: Mosby, Inc.

-Rashid, S.J. (1998). Some Genetic Aspects of Thalassemia in Erbil Province. Thesis.

-Bouroncle, B.A and Doan, C.A. (1964). Cooley's anaemia: Indications for Splenectomy. Ann.NY.Acad. Sci. 119:709-721.

-Kaplan M, C. Hammerman, H. J. Vreman, R. J. Wong and D. K. Stevenson.(2008): Severe hemolysis with normal blood count in a glucose-6-phosphate dehydrogenase deficient neonateHemolysis with normal blood count. Journal of Perinatology28, 306-309.

-Clarke, G.M and Higgins T.N. (2000). Laboratory Investigation of Hemoglobinopathies and Thalassemias: Review and Update. Clinical chemistry.p 46:8:1284-1290.

-Pagana, K.D., & Pagana, T.J. (2002). Mosby's diagnostic and laboratory test reference (6th ed.). St. Louis: Mosby-Year Book, Inc.

-Unchern, S.; Laoharuangpanya, N.; Phumala, N.; Sipankapracha, P.; Pootraakul, P.; Fucharoen, S.; Wanachivanawin, W.; and Chantharaksri, U., (2003).The Effects of Vitamin E on Platelet Activity in β-thalassemia Patients. British J. Haematology. 123;736-744.

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Published

2024-11-22

How to Cite

Abid, Q. H. (2024). Effect of hyperbilirubinemia on Some Physiological parameters in infantile in Karbala city. OBAT: Jurnal Riset Ilmu Farmasi Dan Kesehatan, 2(6), 288–296. https://doi.org/10.61132/obat.v2i6.879

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